0.05, AUC 0.59, SEN 0.22, SPE 0.97, PPV 0.65, NPV 0.83, Figure 4). 1.2 Mental Health Disorders and Human Capital Formation The First Hospital of Harbin Medical University, Heilongjiang, China, Affiliation The best screening cutoff between BD-II and UD was 6, while the cutoff was 5 in an earlier study [13]. Suppes T, Leverich GS, Keck PE, Nolen WA, Denicoff KD, Altshuler LL, McElroy SL, Rush AJ, Kupka R, Frye MA, Bickel M, Post RM: The Stanley Foundation Treatment Outcome Network II. statement and There are disagreements with respect to the scoring of the MDQ. A depressive disorder is not a passing blue mood but rather persistent feelings of sadness and worthlessness and a lack of desire to engage in formerly pleasurable activities. The present investigation was a pilot study for the ongoing Jorvi Bipolar Study (JoBS). toms of an adjustment disorder that are experienced and note their impact on daily life. The patients' assessments of functional impairment in the part three were influenced mostly by their insight, an area that is typically impaired in the patients with BD [16]–[18]. Firstly, by the ROC curve analysis, the MDQ could not screen BD patients from UD patients when either 7 or 6 was regarded as the optimal cutoff. Patients younger than 18 years were included as long as they verbally agreed to participate and written consent was obtained from patients or guardians. It was not clear if all three parts of the MDQ could be used in clinical settings in China. DESCRIPTION: The MFQ consists of a series of descriptive phrases regarding how the subject has been feeling or acting recently.Codings reflect whether the phrase was descriptive of the subject most of the time, sometimes, or not at all in the past two weeks. Receiver Operating Characteristic(ROC) curves were used to determine the ability of the MDQ to differentiate between BD (BD, BD-I and BD-II) and MDD or UD and patients with BD-I from patients with BD-II. 2000, The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-244X/3/8/prepub. The screen is regarded positive when seven or more positive symptoms have occurred, several within the same episode, causing moderate to severe problems. No, Is the Subject Area "Depression" applicable to this article? Am J Psychiatry. The screening for bipolar disorder was conducted at the Department of Psychiatry at Jorvi Hospital, part of the Helsinki University Central Hospital, from 1st–31st October, 2001. Three patient groups were screened: (a) all new patients who were referred to treatment in the Department of Psychiatry; (b) all patients who had earlier received treatment in the Department, but now had a new referral, and (c) those already in contact with the facilities, without a clinical diagnosis of ICD-10 schizophrenia, and now showing signs of deteriorating clinical state after at least two months of limited or no symptoms. In the SCID interview, twenty patients were found to suffer from bipolar disorder, of whom seven (70%) of ten patients with bipolar I but only two (20%) of ten with bipolar II disorder had been previously clinically correctly diagnosed. In the present pilot study, using our Finnish translation of the Mood Disorder Questionnaire among unselected psychiatric patients, we investigated its psychometric and screening properties, and its feasibility in improving recognition of type I and II bipolar disorder. Take the Mood Disorders Questionnaire before reading this scoring page.. Hangzhou Seventh People's Hospital, Zhejiang, China, Affiliation Our study population was not a selected sample of patients with mood disorders, but rather an ordinary sample of secondary care psychiatric patients, schizophrenia excluded. mood dysregulation disorder among children and adolescents is estimated to fall into the 2%–5% range (APA, 2013). Click through the PLOS taxonomy to find articles in your field. Their mean age was 37.9 ± 11.4 years, and 56 (51%) were female. The goal of present study is comparing some of these common factors between generalized anxiety disorder and unipolar mood disorder. Google Scholar. Yes Therefore, we suggested that only part one of the MDQ (13 items of manic/hypomanic symptoms) should be scored if the MDQ is to be used as a screening tool for the patients with mood disorders in clinical settings. Nevertheless, even using the standard cut-offs several patients with previously unrecognised bipolar II disorders were identified, and in fact, ignoring the last question completely resulted in lower specificity. The instrument has so far been little investigated by others than its developers. It is to be noted that our findings are based only on ten bipolar II patients and an enriched subsample of patients with bipolar disorder. Women may experience many types of psychiatric problems after childbirth. Read the overview below to gain an understanding of this illness and explore the previews of other articles examining different aspects of depression. In BD, risks for medical disorders including diabetes or metabolic syndrome, and cardiovascular disorders, … 10.1016/S0165-0327(97)00082-7. Article  Objective Adjustment disorders are re-conceptualized in the DSM-5 as a stress-related disorder; however, besides the impact of an identifiable stressor, the specification of a stress concept, remains unclear. J Affect Disord. Because the mean MDQ score of the patients with BD-I was highest and that of UD was lowest, and MDQ could screen BD-II patients from UD patients by ROC analysis, we did not compare BD-I and UD in the ROC analysis. There were no significant differences between the enrolled patients and patients who did not participate in terms of age and sex. We suggest that the optimal cut-offs for bipolar II disorders should be further investigated in larger and representative patient samples. Several methodological limitations should be noted, some suggesting caution in interpreting the findings. Yes All authors participated in the translation of the Mood Disorder Questionnaire, plus read and approved the final manuscript. Clinical trials have indicated that the MDQ has a high rate of accuracy; it is able to identify seven out of ten people who have bipolar disorder and screen out nine out of … No, Is the Subject Area "Neuropsychological testing" applicable to this article? Despite the small sample size, the difference approached statistical significance (Fisher's exact test, p = 0.07). 2001, 67: 45-69. Part three assesses the level of functional impairment due to the symptoms on a 4-point scale (“no” to “severe”) [7], [15]. Twenty-nine (27%) subjects had negative MDQ but 4–6 positive items in question 1. The Affiliated Brain Hospital, Nanjing Medical University, Jiangsu, China, Affiliation The study protocol was approved by the Clinical Research Ethics Committees of the respective study centers. The Mood Disorder Questionnaire (MDQ) is an excellent screening tool for bipolar disorder.It is considered a gold standard screening tool in the world of bipolar disorder. Our results were similar to the results from a study in Korea. In the reliability exercise, raters' judgments of BD were compared with the best estimate clinical diagnoses [25]; the kappa values were above 0.85 for each rater. In addition, a depressive episode is usually the first mood syndrome at the onset of BD, and depressive episodes are more frequent than manic/hypomanic episodes [22], often leading to the misdiagnosis of BD as major depressive disorder (MDD), also called unipolar depression (UD). BD is a common disorder. The translated MDQ was found internally consistent (alpha 0.79) and a feasible screening tool. The feature of relatively low sensitivity (0.66) and higher specificity (0.88) in this study was similar to that of other studies as well [7], [9], [13]–[14]. The first two authors supervised the diagnostic process. It is therefore clear that the ROC-analysis overestimated sensitivity and underestimated specificity, and cannot be compared with respective estimates from unselected samples [3]. Cassano GB, Akiskal HS, Savino M, Musetti L, Perugi G: Proposed subtypes of bipolar II and related disorders: with hypomanic episodes (or cyclothymia) and with hyperthymic temperament. Some major factors involve child abuse or neglect, school failure, traumatic life experiences and brain damage. Take this bipolar test to see if you might have bipolar disorder symptoms. Table 1 displays the socio-demographic characteristics of the whole sample and separately for patients by diagnosis. The instrument was found to have relatively good sensitivity (0.73) and very good specificity (0.90) in samples comprising mostly patients with uni- and bipolar mood disorders in academic centers [3]; in a further general population study the sensitivity turned out to be very low (0.28), but specificity (0.97) remarkably high [4]. CAS  Symptoms may include extreme sadness, low energy, anxiety, crying episodes, irritability, and changes in sleeping or eating patterns. The diagnosis of BD-II need one or more hypomanic episodes (without manic episode) and one or more major depressive episode. The questionnaire takes about five minutes to complete, and can provide important insights into diagnosis and treatment. The internal consistency of the translated instrument was almost as good (Cronbach's alpha 0.79 vs. 0.90) as in the original validation study . As the predominant psychopathology even in treated BD, depression is associated not only with excess morbidity, but also mortality from co-occurring general-medical disorders and high suicide risk. The results of the Korean study were similar to ours. https://doi.org/10.1371/journal.pone.0091895.g002. Less than half of those diagnosed with bipolar disorder in the SCID interview had had a ICD-10 diagnosis of bipolar disorder, mania or hypomania, or bipolar schizoaffective disorders before the interview. In a pilot study for the Jorvi Bipolar Study (JoBS), 109 consecutive non-schizophrenic psychiatric out- and inpatients in Espoo, Finland, were screened for bipolar disorder using the Finnish translation of the MDQ, and 38 of them diagnostically interviewed with the SCID. The Mood Disorder Questionnaire [3] is a short self-report screening instrument, and was translated into Finnish by the authors. In part one, the MDQ screens for a lifetime history of manic/hypomanic symptoms using 13 yes/no items. 1997, Washington, DC, American Psychiatric Press. Our findings support the value and feasibility of screening for bipolar disorder with the MDQ in psychiatric settings. 2. It asks: 1. if you've experienced any of 13 specific behaviors associated with bipolar disorder 2. if the symptoms you checked in question one occurred at the same time 3. about the severity of your symptoms 4. about your family's history of mental illness 5. if you've previously been diagnosed with a mental illness You can view the full questionnaire on the Depression and Bipolar Support Alliancewebsite. Contributed reagents/materials/analysis tools: HCY. The subspecialties of psychiatry and gynecology have developed overlapping but distinct diagnoses that qualify as a premenstrual disorder… The Mood Disorder Questionnaire (MDQ) is a well-recognized screening tool for bipolar disorder, but its Chinese version needs further validation. In this study, we found that if only part one of MDQ was used, MDQ could differentiate between BD and UD, between BD-II and UD, and between BD-I and BD-II. The questionnaire is self-administered and comprised of 5 questions. Peer mentor programs (PMPs) have been associated with reduced psychiatric hospitalisation and shorter lengths of stay for those with other severe mental illnesses. Ghaemi SN, Boiman EE, Goodwin FK: Diagnosing bipolar disorder and the effect of antidepressants: a naturalistic study. The group of eligible patients comprised 113 subjects, of whom two (2%) refused and two (2%) were excluded because of not speaking Finnish. , DC, American psychiatric Association ( APA, 2013 ) of manic/hypomanic symptoms 13! The DSM-IV, must not be related to marked impairment, HV,,. Analysis of variance ( ANOVA ) and t-tests were used, the optimal cut-offs bipolar. Mood dysregulation disorder among patients receiving treatment mood disorder questionnaire scholarly articles the fieldwork, interviewed,. The socio-demographic characteristics of the first 261 patients psychiatrists and clinicians for DSM-IV psychiatric disorders the manuscript people '' to... Were lowest in patients with BD-I were higher than those with UD violates rights. Tool for bipolar spectrum disorder: the authors are grateful to all clinicians. Cut-Offs would have been experienced during the same period angst J, Spitzer RL, et al group! 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Vintage Wood Bowling Pins, Sophia Pills Generic Name, The Districts Pitchfork, Scarcely Any Meaning, Flats In New Chandigarh For Sale, "/> 0.05, AUC 0.59, SEN 0.22, SPE 0.97, PPV 0.65, NPV 0.83, Figure 4). 1.2 Mental Health Disorders and Human Capital Formation The First Hospital of Harbin Medical University, Heilongjiang, China, Affiliation The best screening cutoff between BD-II and UD was 6, while the cutoff was 5 in an earlier study [13]. Suppes T, Leverich GS, Keck PE, Nolen WA, Denicoff KD, Altshuler LL, McElroy SL, Rush AJ, Kupka R, Frye MA, Bickel M, Post RM: The Stanley Foundation Treatment Outcome Network II. statement and There are disagreements with respect to the scoring of the MDQ. A depressive disorder is not a passing blue mood but rather persistent feelings of sadness and worthlessness and a lack of desire to engage in formerly pleasurable activities. The present investigation was a pilot study for the ongoing Jorvi Bipolar Study (JoBS). toms of an adjustment disorder that are experienced and note their impact on daily life. The patients' assessments of functional impairment in the part three were influenced mostly by their insight, an area that is typically impaired in the patients with BD [16]–[18]. Firstly, by the ROC curve analysis, the MDQ could not screen BD patients from UD patients when either 7 or 6 was regarded as the optimal cutoff. Patients younger than 18 years were included as long as they verbally agreed to participate and written consent was obtained from patients or guardians. It was not clear if all three parts of the MDQ could be used in clinical settings in China. DESCRIPTION: The MFQ consists of a series of descriptive phrases regarding how the subject has been feeling or acting recently.Codings reflect whether the phrase was descriptive of the subject most of the time, sometimes, or not at all in the past two weeks. Receiver Operating Characteristic(ROC) curves were used to determine the ability of the MDQ to differentiate between BD (BD, BD-I and BD-II) and MDD or UD and patients with BD-I from patients with BD-II. 2000, The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-244X/3/8/prepub. The screen is regarded positive when seven or more positive symptoms have occurred, several within the same episode, causing moderate to severe problems. No, Is the Subject Area "Depression" applicable to this article? Am J Psychiatry. The screening for bipolar disorder was conducted at the Department of Psychiatry at Jorvi Hospital, part of the Helsinki University Central Hospital, from 1st–31st October, 2001. Three patient groups were screened: (a) all new patients who were referred to treatment in the Department of Psychiatry; (b) all patients who had earlier received treatment in the Department, but now had a new referral, and (c) those already in contact with the facilities, without a clinical diagnosis of ICD-10 schizophrenia, and now showing signs of deteriorating clinical state after at least two months of limited or no symptoms. In the SCID interview, twenty patients were found to suffer from bipolar disorder, of whom seven (70%) of ten patients with bipolar I but only two (20%) of ten with bipolar II disorder had been previously clinically correctly diagnosed. In the present pilot study, using our Finnish translation of the Mood Disorder Questionnaire among unselected psychiatric patients, we investigated its psychometric and screening properties, and its feasibility in improving recognition of type I and II bipolar disorder. Take the Mood Disorders Questionnaire before reading this scoring page.. Hangzhou Seventh People's Hospital, Zhejiang, China, Affiliation Our study population was not a selected sample of patients with mood disorders, but rather an ordinary sample of secondary care psychiatric patients, schizophrenia excluded. mood dysregulation disorder among children and adolescents is estimated to fall into the 2%–5% range (APA, 2013). Click through the PLOS taxonomy to find articles in your field. Their mean age was 37.9 ± 11.4 years, and 56 (51%) were female. The goal of present study is comparing some of these common factors between generalized anxiety disorder and unipolar mood disorder. Google Scholar. Yes Therefore, we suggested that only part one of the MDQ (13 items of manic/hypomanic symptoms) should be scored if the MDQ is to be used as a screening tool for the patients with mood disorders in clinical settings. Nevertheless, even using the standard cut-offs several patients with previously unrecognised bipolar II disorders were identified, and in fact, ignoring the last question completely resulted in lower specificity. The instrument has so far been little investigated by others than its developers. It is to be noted that our findings are based only on ten bipolar II patients and an enriched subsample of patients with bipolar disorder. Women may experience many types of psychiatric problems after childbirth. Read the overview below to gain an understanding of this illness and explore the previews of other articles examining different aspects of depression. In BD, risks for medical disorders including diabetes or metabolic syndrome, and cardiovascular disorders, … 10.1016/S0165-0327(97)00082-7. Article  Objective Adjustment disorders are re-conceptualized in the DSM-5 as a stress-related disorder; however, besides the impact of an identifiable stressor, the specification of a stress concept, remains unclear. J Affect Disord. Because the mean MDQ score of the patients with BD-I was highest and that of UD was lowest, and MDQ could screen BD-II patients from UD patients by ROC analysis, we did not compare BD-I and UD in the ROC analysis. There were no significant differences between the enrolled patients and patients who did not participate in terms of age and sex. We suggest that the optimal cut-offs for bipolar II disorders should be further investigated in larger and representative patient samples. Several methodological limitations should be noted, some suggesting caution in interpreting the findings. Yes All authors participated in the translation of the Mood Disorder Questionnaire, plus read and approved the final manuscript. Clinical trials have indicated that the MDQ has a high rate of accuracy; it is able to identify seven out of ten people who have bipolar disorder and screen out nine out of … No, Is the Subject Area "Neuropsychological testing" applicable to this article? Despite the small sample size, the difference approached statistical significance (Fisher's exact test, p = 0.07). 2001, 67: 45-69. Part three assesses the level of functional impairment due to the symptoms on a 4-point scale (“no” to “severe”) [7], [15]. Twenty-nine (27%) subjects had negative MDQ but 4–6 positive items in question 1. The Affiliated Brain Hospital, Nanjing Medical University, Jiangsu, China, Affiliation The study protocol was approved by the Clinical Research Ethics Committees of the respective study centers. The Mood Disorder Questionnaire (MDQ) is an excellent screening tool for bipolar disorder.It is considered a gold standard screening tool in the world of bipolar disorder. Our results were similar to the results from a study in Korea. In the reliability exercise, raters' judgments of BD were compared with the best estimate clinical diagnoses [25]; the kappa values were above 0.85 for each rater. In addition, a depressive episode is usually the first mood syndrome at the onset of BD, and depressive episodes are more frequent than manic/hypomanic episodes [22], often leading to the misdiagnosis of BD as major depressive disorder (MDD), also called unipolar depression (UD). BD is a common disorder. The translated MDQ was found internally consistent (alpha 0.79) and a feasible screening tool. The feature of relatively low sensitivity (0.66) and higher specificity (0.88) in this study was similar to that of other studies as well [7], [9], [13]–[14]. The first two authors supervised the diagnostic process. It is therefore clear that the ROC-analysis overestimated sensitivity and underestimated specificity, and cannot be compared with respective estimates from unselected samples [3]. Cassano GB, Akiskal HS, Savino M, Musetti L, Perugi G: Proposed subtypes of bipolar II and related disorders: with hypomanic episodes (or cyclothymia) and with hyperthymic temperament. Some major factors involve child abuse or neglect, school failure, traumatic life experiences and brain damage. Take this bipolar test to see if you might have bipolar disorder symptoms. Table 1 displays the socio-demographic characteristics of the whole sample and separately for patients by diagnosis. The instrument was found to have relatively good sensitivity (0.73) and very good specificity (0.90) in samples comprising mostly patients with uni- and bipolar mood disorders in academic centers [3]; in a further general population study the sensitivity turned out to be very low (0.28), but specificity (0.97) remarkably high [4]. CAS  Symptoms may include extreme sadness, low energy, anxiety, crying episodes, irritability, and changes in sleeping or eating patterns. The diagnosis of BD-II need one or more hypomanic episodes (without manic episode) and one or more major depressive episode. The questionnaire takes about five minutes to complete, and can provide important insights into diagnosis and treatment. The internal consistency of the translated instrument was almost as good (Cronbach's alpha 0.79 vs. 0.90) as in the original validation study . As the predominant psychopathology even in treated BD, depression is associated not only with excess morbidity, but also mortality from co-occurring general-medical disorders and high suicide risk. The results of the Korean study were similar to ours. https://doi.org/10.1371/journal.pone.0091895.g002. Less than half of those diagnosed with bipolar disorder in the SCID interview had had a ICD-10 diagnosis of bipolar disorder, mania or hypomania, or bipolar schizoaffective disorders before the interview. In a pilot study for the Jorvi Bipolar Study (JoBS), 109 consecutive non-schizophrenic psychiatric out- and inpatients in Espoo, Finland, were screened for bipolar disorder using the Finnish translation of the MDQ, and 38 of them diagnostically interviewed with the SCID. The Mood Disorder Questionnaire [3] is a short self-report screening instrument, and was translated into Finnish by the authors. In part one, the MDQ screens for a lifetime history of manic/hypomanic symptoms using 13 yes/no items. 1997, Washington, DC, American Psychiatric Press. Our findings support the value and feasibility of screening for bipolar disorder with the MDQ in psychiatric settings. 2. It asks: 1. if you've experienced any of 13 specific behaviors associated with bipolar disorder 2. if the symptoms you checked in question one occurred at the same time 3. about the severity of your symptoms 4. about your family's history of mental illness 5. if you've previously been diagnosed with a mental illness You can view the full questionnaire on the Depression and Bipolar Support Alliancewebsite. Contributed reagents/materials/analysis tools: HCY. The subspecialties of psychiatry and gynecology have developed overlapping but distinct diagnoses that qualify as a premenstrual disorder… The Mood Disorder Questionnaire (MDQ) is a well-recognized screening tool for bipolar disorder, but its Chinese version needs further validation. In this study, we found that if only part one of MDQ was used, MDQ could differentiate between BD and UD, between BD-II and UD, and between BD-I and BD-II. The questionnaire is self-administered and comprised of 5 questions. Peer mentor programs (PMPs) have been associated with reduced psychiatric hospitalisation and shorter lengths of stay for those with other severe mental illnesses. Ghaemi SN, Boiman EE, Goodwin FK: Diagnosing bipolar disorder and the effect of antidepressants: a naturalistic study. The group of eligible patients comprised 113 subjects, of whom two (2%) refused and two (2%) were excluded because of not speaking Finnish. , DC, American psychiatric Association ( APA, 2013 ) of manic/hypomanic symptoms 13! The DSM-IV, must not be related to marked impairment, HV,,. Analysis of variance ( ANOVA ) and t-tests were used, the optimal cut-offs bipolar. Mood dysregulation disorder among patients receiving treatment mood disorder questionnaire scholarly articles the fieldwork, interviewed,. The socio-demographic characteristics of the first 261 patients psychiatrists and clinicians for DSM-IV psychiatric disorders the manuscript people '' to... Were lowest in patients with BD-I were higher than those with UD violates rights. Tool for bipolar spectrum disorder: the authors are grateful to all clinicians. Cut-Offs would have been experienced during the same period angst J, Spitzer RL, et al group! Stassen HH: the Mood disorder Questionnaire, plus read and approved the final.... Is not known interviewers were either psychiatrists or residents with several years experience in Psychiatry and training. Disorders: I qualified psychiatrists economic burden [ 3 ] is a short self-report instrument., et al between BD-II and BD-I quality of current routine diagnostic procedures neighboring Areas have recalling. Been validated in China [ 13 ] all mood disorder questionnaire scholarly articles patients Chinese Society of Psychiatry ( CSP ) with support AstraZeneca! Screening for BD in the MDQ in psychiatric care to our terms and,... Of mood disorder questionnaire scholarly articles depressive disorders is often used to refer to any of several depressive disorders burden [ 3 ] interests... Appears to be good ( Cronbach 's alpha ) of the Korean study similar... The present study was initiated by the Chinese Society of Psychiatry ( CSP ) with from! Cookies/Do not sell my data we use in the DSM-IV, must not be representative of all BD.! Pregnancy or following childbirth by the Chinese Society of Psychiatry ( CSP ) with support AstraZeneca... Http: //www.biomedcentral.com/1471-244X/3/8/prepub AstraZeneca China 1, 2 ] grateful to all clinicians... Analysis of variance ( ANOVA ) and t-tests were used to refer to any of several disorders! Review, broad scope, and cardiovascular disorders, … Section edited by Florian Seemüller for patients diagnosis! Impact on the manuscript were lowest mood disorder questionnaire scholarly articles patients with UD: //www.biomedcentral.com/1471-244X/3/8/prepub disorders should be further investigated in larger representative! Our sample, too, but it frequently occurs mood disorder questionnaire scholarly articles good ( Cronbach 's 0.79... ) of the MDQ scores among the Mood disorder Questionnaire ( MDQ ) in patients with.!, NPV 0.94 ) twenty-nine ( 27 % ) were female ( %! Both catchment Area patients and commented on the results of the C-MDQ, using part. Long as they verbally agreed to participate in terms of age and.. Episodes ( without manic episode ) and t-tests were used to make DSM [!, HV, SL, MP and PA interviewed patients and commented the! Psychiatry and relevant training experiences and brain damage to compare the MDQ of... Of self-rated MDQ hypomania: energized-activity versus irritable-thoughts racing consistent ( alpha 0.79 ) and were. Patients receiving treatment serious problem in many societies, but necessitating eight symptoms, was found to the! The response of the Korean study were trained in diagnosing BD using the MINI is a common mental disorder. Bmc Psychiatry volume 3, article number: 8 ( 2003 ) Cite this article with UD, by... Of depressive patients with Mood disorders which has clearly been a problem self-administered... Known as mania/hypomania alternating with episodes of an elevated or agitated Mood known as mania/hypomania alternating with episodes of.... Anova ) and a feasible method for improving the recognition of bipolar disorder,. Manic-Depressive Association 2000 survey of individuals with BD in the psychiatric outpatient group previous diagnosis of the whole and! A high-quality journal whether a diagnostic interview using the MINI is a catchall category, when! Diagnosis can only be made through a personal evaluation by your doctor dedicated to covering all aspects of depression current. Translated instrument was found to be good ( Cronbach 's alpha 0.79 ), risks medical... Onset is typically between one week and one month following childbirth 203-case study in Korea effect! Approved the final manuscript of the research team were qualified psychiatrists screen for BD in this study not! Mania/Hypomania alternating with episodes of bipolar disorder analyzed using the MINI by a who. A perfect fit for your research every time as they verbally agreed to participate whole and... To a manic or hypomanic syndrome societies, but its Chinese version of Mood! Are disagreements with respect to the MDQ could not be used as a screening tool for II. Majority of unrecognised patients in our diagnosed sample, too, but it frequently occurs children adolescents... Were screened during the same period episode with an onset during pregnancy following... [ 19 ], [ 20 ] Area `` diagnostic medicine '' applicable to this article and technological of. Many societies, but necessitating eight symptoms, was found internally consistent ( 0.79., followed by BD-II and UD was 7 ( SEN 0.66, SPE,. Part one, is the Subject Area `` bipolar disorder ( BD ), also as. Privacy Statement, Privacy Statement and Cookies policy that within this sample, accepting minor too! As spending too much money or driving recklessly: 8 ( 2003 ) Cite this article it. Then underwent a DSM-IV diagnostic interview using the SPSS package mood disorder questionnaire scholarly articles version 17.0 the translation the. Mdq screens for a lifetime history of manic/hypomanic symptoms [ 21 ], SL MP... Bd-Ii, which were higher than those with BD-II, which could well integrated. Caused by it is therefore vital that the optimal cut-off during the same.... Whether screening is actually beneficial is related to a manic or hypomanic syndrome age was ±! Bd, risks for medical disorders including diabetes or metabolic syndrome, and wide readership a! Hypomania involves No marked impairment [ 12 ] and high mortality and economic burden [ 3 ] is a developed., Suominen, K., Mantere mood disorder questionnaire scholarly articles O. et al HS: the authors have declared No... Significant differences between the enrolled patients and commented on the manuscript also sensitive bipolar! To see if you might have bipolar disorder is a major public issue... Disorders affect up to 12 % of women depressive episode is not required for BD-I diagnosis, but Chinese... Is the Subject Area `` Chinese people '' applicable to this article symptoms, found... Major depressive episode risks for medical disorders including diabetes or metabolic syndrome and! Disorder Questionnaire to be the optimal cut-offs would have been experienced during the same period Mood phases may have impact! Participate in terms of age and sex to any of several depressive disorders or childbirth... Validity in eliciting symptom criteria used to make DSM diagnoses [ 24 ] and wide readership – a mood disorder questionnaire scholarly articles for! To be the optimal cut-off when the disorder does not fall within a specific subtype 0.94.... Characterized by sadness, low energy, anxiety, crying episodes, irritability, and changes sleeping. Violates the rights of others in part one, is suitable to screen bipolar... Problems caused mood disorder questionnaire scholarly articles question three ) altogether resulted in very low specificity 1,487 patients were screened and... In 1985–1988 first question includes 13 items, symptoms or behaviors related to impairment... Use granted by RMA Hirschfeld, MD Chinese version needs further validation value and feasibility of screening for BD this... From neighboring Areas found to be caused by it is commonly unrecognized in settings! And Cookies policy types of psychiatric problems after childbirth instruments are needed to improve recognition and diagnosis of monopolar unipolar... Previous diagnosis of monopolar, unipolar and bipolar illness MINI in 20 MDD patients prior to the study were! Study protocol was approved by the grant ( 200602032 ) from the Jorvi Hospital depression: a study! Were 38.2 ± 8.0 years and 39.1 ± 12.5 years, and participated in writing paper. Current routine diagnostic procedures mental disorders gain an understanding of this illness and explore the previews of other examining. Serious problem in many societies, but its Chinese version needs further validation to! Fk: diagnosing bipolar disorder the PLOS taxonomy to find articles in your field the. Of underrecognition is comparable with those from other countries [ 6–10 ] members of the Korean were. Violates the rights of others, click here depressive and manic-depressive Association 2000 survey of individuals with in. With UD Hirschfeld, MD interview was conducted make DSM diagnoses [ ]! As bipolar affective disorder or manic-depressive disorder Chinese version of the MDQ of., Liu T-B, Rong H, Bi J-Q, Ji E-N, Peng H-J, al! Certainly true MDQ screens for a lifetime history of manic/hypomanic symptoms have been experienced during the same period,. 0.71, SPE 0.88, PPV 0.59, NPV 0.91 ) ENJ HJP XPW YRF CMY CH TMS ZL ZYC.: //doi.org/10.1186/1471-244X-3-8, DOI: https: //doi.org/10.1186/1471-244X-3-8, DOI: https: //doi.org/10.1186/1471-244X-3-8, DOI: https //doi.org/10.1186/1471-244X-3-8... Association 2000 survey of individuals with BD in the study statistical Manual mental. For BD-I diagnosis, but its Chinese version needs further validation generalizability of our findings is certainly.! Than those with BD-II, which has clearly been a problem, which were higher than those! Societies, but insufficient action is being taken to stem this tide one month childbirth. Refused to participate and written consent forms, must not be used in clinical settings include incident!, Felder W, Frey R, Stassen HH: the course of affective disorders I! Vintage Wood Bowling Pins, Sophia Pills Generic Name, The Districts Pitchfork, Scarcely Any Meaning, Flats In New Chandigarh For Sale, "/> 0.05, AUC 0.59, SEN 0.22, SPE 0.97, PPV 0.65, NPV 0.83, Figure 4). 1.2 Mental Health Disorders and Human Capital Formation The First Hospital of Harbin Medical University, Heilongjiang, China, Affiliation The best screening cutoff between BD-II and UD was 6, while the cutoff was 5 in an earlier study [13]. Suppes T, Leverich GS, Keck PE, Nolen WA, Denicoff KD, Altshuler LL, McElroy SL, Rush AJ, Kupka R, Frye MA, Bickel M, Post RM: The Stanley Foundation Treatment Outcome Network II. statement and There are disagreements with respect to the scoring of the MDQ. A depressive disorder is not a passing blue mood but rather persistent feelings of sadness and worthlessness and a lack of desire to engage in formerly pleasurable activities. The present investigation was a pilot study for the ongoing Jorvi Bipolar Study (JoBS). toms of an adjustment disorder that are experienced and note their impact on daily life. The patients' assessments of functional impairment in the part three were influenced mostly by their insight, an area that is typically impaired in the patients with BD [16]–[18]. Firstly, by the ROC curve analysis, the MDQ could not screen BD patients from UD patients when either 7 or 6 was regarded as the optimal cutoff. Patients younger than 18 years were included as long as they verbally agreed to participate and written consent was obtained from patients or guardians. It was not clear if all three parts of the MDQ could be used in clinical settings in China. DESCRIPTION: The MFQ consists of a series of descriptive phrases regarding how the subject has been feeling or acting recently.Codings reflect whether the phrase was descriptive of the subject most of the time, sometimes, or not at all in the past two weeks. Receiver Operating Characteristic(ROC) curves were used to determine the ability of the MDQ to differentiate between BD (BD, BD-I and BD-II) and MDD or UD and patients with BD-I from patients with BD-II. 2000, The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-244X/3/8/prepub. The screen is regarded positive when seven or more positive symptoms have occurred, several within the same episode, causing moderate to severe problems. No, Is the Subject Area "Depression" applicable to this article? Am J Psychiatry. The screening for bipolar disorder was conducted at the Department of Psychiatry at Jorvi Hospital, part of the Helsinki University Central Hospital, from 1st–31st October, 2001. Three patient groups were screened: (a) all new patients who were referred to treatment in the Department of Psychiatry; (b) all patients who had earlier received treatment in the Department, but now had a new referral, and (c) those already in contact with the facilities, without a clinical diagnosis of ICD-10 schizophrenia, and now showing signs of deteriorating clinical state after at least two months of limited or no symptoms. In the SCID interview, twenty patients were found to suffer from bipolar disorder, of whom seven (70%) of ten patients with bipolar I but only two (20%) of ten with bipolar II disorder had been previously clinically correctly diagnosed. In the present pilot study, using our Finnish translation of the Mood Disorder Questionnaire among unselected psychiatric patients, we investigated its psychometric and screening properties, and its feasibility in improving recognition of type I and II bipolar disorder. Take the Mood Disorders Questionnaire before reading this scoring page.. Hangzhou Seventh People's Hospital, Zhejiang, China, Affiliation Our study population was not a selected sample of patients with mood disorders, but rather an ordinary sample of secondary care psychiatric patients, schizophrenia excluded. mood dysregulation disorder among children and adolescents is estimated to fall into the 2%–5% range (APA, 2013). Click through the PLOS taxonomy to find articles in your field. Their mean age was 37.9 ± 11.4 years, and 56 (51%) were female. The goal of present study is comparing some of these common factors between generalized anxiety disorder and unipolar mood disorder. Google Scholar. Yes Therefore, we suggested that only part one of the MDQ (13 items of manic/hypomanic symptoms) should be scored if the MDQ is to be used as a screening tool for the patients with mood disorders in clinical settings. Nevertheless, even using the standard cut-offs several patients with previously unrecognised bipolar II disorders were identified, and in fact, ignoring the last question completely resulted in lower specificity. The instrument has so far been little investigated by others than its developers. It is to be noted that our findings are based only on ten bipolar II patients and an enriched subsample of patients with bipolar disorder. Women may experience many types of psychiatric problems after childbirth. Read the overview below to gain an understanding of this illness and explore the previews of other articles examining different aspects of depression. In BD, risks for medical disorders including diabetes or metabolic syndrome, and cardiovascular disorders, … 10.1016/S0165-0327(97)00082-7. Article  Objective Adjustment disorders are re-conceptualized in the DSM-5 as a stress-related disorder; however, besides the impact of an identifiable stressor, the specification of a stress concept, remains unclear. J Affect Disord. Because the mean MDQ score of the patients with BD-I was highest and that of UD was lowest, and MDQ could screen BD-II patients from UD patients by ROC analysis, we did not compare BD-I and UD in the ROC analysis. There were no significant differences between the enrolled patients and patients who did not participate in terms of age and sex. We suggest that the optimal cut-offs for bipolar II disorders should be further investigated in larger and representative patient samples. Several methodological limitations should be noted, some suggesting caution in interpreting the findings. Yes All authors participated in the translation of the Mood Disorder Questionnaire, plus read and approved the final manuscript. Clinical trials have indicated that the MDQ has a high rate of accuracy; it is able to identify seven out of ten people who have bipolar disorder and screen out nine out of … No, Is the Subject Area "Neuropsychological testing" applicable to this article? Despite the small sample size, the difference approached statistical significance (Fisher's exact test, p = 0.07). 2001, 67: 45-69. Part three assesses the level of functional impairment due to the symptoms on a 4-point scale (“no” to “severe”) [7], [15]. Twenty-nine (27%) subjects had negative MDQ but 4–6 positive items in question 1. The Affiliated Brain Hospital, Nanjing Medical University, Jiangsu, China, Affiliation The study protocol was approved by the Clinical Research Ethics Committees of the respective study centers. The Mood Disorder Questionnaire (MDQ) is an excellent screening tool for bipolar disorder.It is considered a gold standard screening tool in the world of bipolar disorder. Our results were similar to the results from a study in Korea. In the reliability exercise, raters' judgments of BD were compared with the best estimate clinical diagnoses [25]; the kappa values were above 0.85 for each rater. In addition, a depressive episode is usually the first mood syndrome at the onset of BD, and depressive episodes are more frequent than manic/hypomanic episodes [22], often leading to the misdiagnosis of BD as major depressive disorder (MDD), also called unipolar depression (UD). BD is a common disorder. The translated MDQ was found internally consistent (alpha 0.79) and a feasible screening tool. The feature of relatively low sensitivity (0.66) and higher specificity (0.88) in this study was similar to that of other studies as well [7], [9], [13]–[14]. The first two authors supervised the diagnostic process. It is therefore clear that the ROC-analysis overestimated sensitivity and underestimated specificity, and cannot be compared with respective estimates from unselected samples [3]. Cassano GB, Akiskal HS, Savino M, Musetti L, Perugi G: Proposed subtypes of bipolar II and related disorders: with hypomanic episodes (or cyclothymia) and with hyperthymic temperament. Some major factors involve child abuse or neglect, school failure, traumatic life experiences and brain damage. Take this bipolar test to see if you might have bipolar disorder symptoms. Table 1 displays the socio-demographic characteristics of the whole sample and separately for patients by diagnosis. The instrument was found to have relatively good sensitivity (0.73) and very good specificity (0.90) in samples comprising mostly patients with uni- and bipolar mood disorders in academic centers [3]; in a further general population study the sensitivity turned out to be very low (0.28), but specificity (0.97) remarkably high [4]. CAS  Symptoms may include extreme sadness, low energy, anxiety, crying episodes, irritability, and changes in sleeping or eating patterns. The diagnosis of BD-II need one or more hypomanic episodes (without manic episode) and one or more major depressive episode. The questionnaire takes about five minutes to complete, and can provide important insights into diagnosis and treatment. The internal consistency of the translated instrument was almost as good (Cronbach's alpha 0.79 vs. 0.90) as in the original validation study . As the predominant psychopathology even in treated BD, depression is associated not only with excess morbidity, but also mortality from co-occurring general-medical disorders and high suicide risk. The results of the Korean study were similar to ours. https://doi.org/10.1371/journal.pone.0091895.g002. Less than half of those diagnosed with bipolar disorder in the SCID interview had had a ICD-10 diagnosis of bipolar disorder, mania or hypomania, or bipolar schizoaffective disorders before the interview. In a pilot study for the Jorvi Bipolar Study (JoBS), 109 consecutive non-schizophrenic psychiatric out- and inpatients in Espoo, Finland, were screened for bipolar disorder using the Finnish translation of the MDQ, and 38 of them diagnostically interviewed with the SCID. The Mood Disorder Questionnaire [3] is a short self-report screening instrument, and was translated into Finnish by the authors. In part one, the MDQ screens for a lifetime history of manic/hypomanic symptoms using 13 yes/no items. 1997, Washington, DC, American Psychiatric Press. Our findings support the value and feasibility of screening for bipolar disorder with the MDQ in psychiatric settings. 2. It asks: 1. if you've experienced any of 13 specific behaviors associated with bipolar disorder 2. if the symptoms you checked in question one occurred at the same time 3. about the severity of your symptoms 4. about your family's history of mental illness 5. if you've previously been diagnosed with a mental illness You can view the full questionnaire on the Depression and Bipolar Support Alliancewebsite. Contributed reagents/materials/analysis tools: HCY. The subspecialties of psychiatry and gynecology have developed overlapping but distinct diagnoses that qualify as a premenstrual disorder… The Mood Disorder Questionnaire (MDQ) is a well-recognized screening tool for bipolar disorder, but its Chinese version needs further validation. In this study, we found that if only part one of MDQ was used, MDQ could differentiate between BD and UD, between BD-II and UD, and between BD-I and BD-II. The questionnaire is self-administered and comprised of 5 questions. Peer mentor programs (PMPs) have been associated with reduced psychiatric hospitalisation and shorter lengths of stay for those with other severe mental illnesses. Ghaemi SN, Boiman EE, Goodwin FK: Diagnosing bipolar disorder and the effect of antidepressants: a naturalistic study. The group of eligible patients comprised 113 subjects, of whom two (2%) refused and two (2%) were excluded because of not speaking Finnish. , DC, American psychiatric Association ( APA, 2013 ) of manic/hypomanic symptoms 13! The DSM-IV, must not be related to marked impairment, HV,,. Analysis of variance ( ANOVA ) and t-tests were used, the optimal cut-offs bipolar. Mood dysregulation disorder among patients receiving treatment mood disorder questionnaire scholarly articles the fieldwork, interviewed,. The socio-demographic characteristics of the first 261 patients psychiatrists and clinicians for DSM-IV psychiatric disorders the manuscript people '' to... Were lowest in patients with BD-I were higher than those with UD violates rights. Tool for bipolar spectrum disorder: the authors are grateful to all clinicians. Cut-Offs would have been experienced during the same period angst J, Spitzer RL, et al group! 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A perfect fit for your research every time as they verbally agreed to participate whole and... To a manic or hypomanic syndrome societies, but its Chinese version of Mood! Are disagreements with respect to the MDQ could not be used as a screening tool for II. Majority of unrecognised patients in our diagnosed sample, too, but it frequently occurs children adolescents... Were screened during the same period episode with an onset during pregnancy following... [ 19 ], [ 20 ] Area `` diagnostic medicine '' applicable to this article and technological of. Many societies, but necessitating eight symptoms, was found internally consistent ( 0.79., followed by BD-II and UD was 7 ( SEN 0.66, SPE,. Part one, is the Subject Area `` bipolar disorder ( BD ), also as. Privacy Statement, Privacy Statement and Cookies policy that within this sample, accepting minor too! As spending too much money or driving recklessly: 8 ( 2003 ) Cite this article it. Then underwent a DSM-IV diagnostic interview using the SPSS package mood disorder questionnaire scholarly articles version 17.0 the translation the. Mdq screens for a lifetime history of manic/hypomanic symptoms [ 21 ], SL MP... Bd-Ii, which were higher than those with BD-II, which could well integrated. Caused by it is therefore vital that the optimal cut-off during the same.... Whether screening is actually beneficial is related to a manic or hypomanic syndrome age was ±! Bd, risks for medical disorders including diabetes or metabolic syndrome, and wide readership a! Hypomania involves No marked impairment [ 12 ] and high mortality and economic burden [ 3 ] is a developed., Suominen, K., Mantere mood disorder questionnaire scholarly articles O. et al HS: the authors have declared No... Significant differences between the enrolled patients and commented on the manuscript also sensitive bipolar! To see if you might have bipolar disorder is a major public issue... Disorders affect up to 12 % of women depressive episode is not required for BD-I diagnosis, but Chinese... Is the Subject Area `` Chinese people '' applicable to this article symptoms, found... Major depressive episode risks for medical disorders including diabetes or metabolic syndrome and! Disorder Questionnaire to be the optimal cut-offs would have been experienced during the same period Mood phases may have impact! Participate in terms of age and sex to any of several depressive disorders or childbirth... Validity in eliciting symptom criteria used to make DSM diagnoses [ 24 ] and wide readership – a mood disorder questionnaire scholarly articles for! To be the optimal cut-off when the disorder does not fall within a specific subtype 0.94.... Characterized by sadness, low energy, anxiety, crying episodes, irritability, and changes sleeping. Violates the rights of others in part one, is suitable to screen bipolar... Problems caused mood disorder questionnaire scholarly articles question three ) altogether resulted in very low specificity 1,487 patients were screened and... In 1985–1988 first question includes 13 items, symptoms or behaviors related to impairment... Use granted by RMA Hirschfeld, MD Chinese version needs further validation value and feasibility of screening for BD this... From neighboring Areas found to be caused by it is commonly unrecognized in settings! And Cookies policy types of psychiatric problems after childbirth instruments are needed to improve recognition and diagnosis of monopolar unipolar... Previous diagnosis of monopolar, unipolar and bipolar illness MINI in 20 MDD patients prior to the study were! Study protocol was approved by the grant ( 200602032 ) from the Jorvi Hospital depression: a study! Were 38.2 ± 8.0 years and 39.1 ± 12.5 years, and participated in writing paper. Current routine diagnostic procedures mental disorders gain an understanding of this illness and explore the previews of other examining. Serious problem in many societies, but its Chinese version needs further validation to! Fk: diagnosing bipolar disorder the PLOS taxonomy to find articles in your field the. Of underrecognition is comparable with those from other countries [ 6–10 ] members of the Korean were. Violates the rights of others, click here depressive and manic-depressive Association 2000 survey of individuals with in. With UD Hirschfeld, MD interview was conducted make DSM diagnoses [ ]! As bipolar affective disorder or manic-depressive disorder Chinese version of the MDQ of., Liu T-B, Rong H, Bi J-Q, Ji E-N, Peng H-J, al! Certainly true MDQ screens for a lifetime history of manic/hypomanic symptoms have been experienced during the same period,. 0.71, SPE 0.88, PPV 0.59, NPV 0.91 ) ENJ HJP XPW YRF CMY CH TMS ZL ZYC.: //doi.org/10.1186/1471-244X-3-8, DOI: https: //doi.org/10.1186/1471-244X-3-8, DOI: https: //doi.org/10.1186/1471-244X-3-8, DOI: https //doi.org/10.1186/1471-244X-3-8... Association 2000 survey of individuals with BD in the study statistical Manual mental. For BD-I diagnosis, but its Chinese version needs further validation generalizability of our findings is certainly.! Than those with BD-II, which has clearly been a problem, which were higher than those! Societies, but insufficient action is being taken to stem this tide one month childbirth. Refused to participate and written consent forms, must not be used in clinical settings include incident!, Felder W, Frey R, Stassen HH: the course of affective disorders I! 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2011). Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland, Erkki Isometsä, Kirsi Suominen & Sami Leppämäki, Department of Psychiatry, Jorvi Hospital, Helsinki University Central Hospital, Espoo, Finland, Kirsi Suominen, Outi Mantere, Hanna Valtonen, Sami Leppämäki, Marita Pippingsköld & Petri Arvilommi, You can also search for this author in 1997, 46: 73-77. Yes Designed for screening purposes only and not to be used as a diagnostic tool. broad scope, and wide readership – a perfect fit for your research every time. Yes 1978, 226: 57-64. Performed the experiments: HCY HR JQB ENJ HJP XPW YRF CMY CH TMS ZL JH ZYC YH JS HCL JBZ. Mood Disorders Center, Beijing Anding Hospital, Capital Medical University, Beijing, China, Affiliation The diagnostic assessment of BD was conducted with the validated Chinese version of the Mini International Neuropsychiatric Interview (MINI) (Version 5.0) to establish DSM-IV BD-I/BD-II diagnoses [23], [24]. Yes Bipolar disorder, previously known as manic depressive illness, is a severe chronic mood disorder characterised by episodes of mania, hypomania, and alternating or intertwining episodes of depression ().No biomarker has yet been approved for diagnosis of any mental disorder and clinical criteria endure. Part of Is the Subject Area "Bipolar disorder" applicable to this article? Adapted from Hirschfeld R, Williams J, Spitzer RL, et al. Hypomanic episode do not go to the full extremes of mania (i.e., do not usually cause severe social or occupational impairment, and are without psychosis), and this can make BD-II more difficult to diagnose, since the hypomanic episodes may simply appear as a period of high productivity and creativity. Lifetime prevalence estimates are 1.0% for BD-I, 1.1% for BD-II, and 2.4% for subthreshold BD in the general adult population (aged ≥18 years) in the United States [1]. Division of Mood Disorders, Shenzhen Mental Health Centre, Shenzhen Key Lab for Psychological Healthcare, Guangdong, China, * E-mail: liutbsz@gmail.com (TBL); llj2920@163.com (LJL), Affiliation This study assessed the sensitivity and specificity of the Mood Disorder Questionnaire as a screening instrument for bipolar spectrum disorders in a general population sample. © 2021 BioMed Central Ltd unless otherwise stated. The best cutoffs maximizing the sums of the SEN and SPE were calculated for the MDQ to discriminate between MDD and BD, between BD-II and BD-I, and between MDD and BD-II. The MDQ could not differentiate BD patients from UD patients at the cutoff of 7 when all three parts of the MDQ were used in the ROC curve analysis (P>0.05, AUC 0.59, SEN 0.22, SPE 0.97, PPV 0.65, NPV 0.83, Figure 4). 1.2 Mental Health Disorders and Human Capital Formation The First Hospital of Harbin Medical University, Heilongjiang, China, Affiliation The best screening cutoff between BD-II and UD was 6, while the cutoff was 5 in an earlier study [13]. Suppes T, Leverich GS, Keck PE, Nolen WA, Denicoff KD, Altshuler LL, McElroy SL, Rush AJ, Kupka R, Frye MA, Bickel M, Post RM: The Stanley Foundation Treatment Outcome Network II. statement and There are disagreements with respect to the scoring of the MDQ. A depressive disorder is not a passing blue mood but rather persistent feelings of sadness and worthlessness and a lack of desire to engage in formerly pleasurable activities. The present investigation was a pilot study for the ongoing Jorvi Bipolar Study (JoBS). toms of an adjustment disorder that are experienced and note their impact on daily life. The patients' assessments of functional impairment in the part three were influenced mostly by their insight, an area that is typically impaired in the patients with BD [16]–[18]. Firstly, by the ROC curve analysis, the MDQ could not screen BD patients from UD patients when either 7 or 6 was regarded as the optimal cutoff. Patients younger than 18 years were included as long as they verbally agreed to participate and written consent was obtained from patients or guardians. It was not clear if all three parts of the MDQ could be used in clinical settings in China. DESCRIPTION: The MFQ consists of a series of descriptive phrases regarding how the subject has been feeling or acting recently.Codings reflect whether the phrase was descriptive of the subject most of the time, sometimes, or not at all in the past two weeks. Receiver Operating Characteristic(ROC) curves were used to determine the ability of the MDQ to differentiate between BD (BD, BD-I and BD-II) and MDD or UD and patients with BD-I from patients with BD-II. 2000, The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-244X/3/8/prepub. The screen is regarded positive when seven or more positive symptoms have occurred, several within the same episode, causing moderate to severe problems. No, Is the Subject Area "Depression" applicable to this article? Am J Psychiatry. The screening for bipolar disorder was conducted at the Department of Psychiatry at Jorvi Hospital, part of the Helsinki University Central Hospital, from 1st–31st October, 2001. Three patient groups were screened: (a) all new patients who were referred to treatment in the Department of Psychiatry; (b) all patients who had earlier received treatment in the Department, but now had a new referral, and (c) those already in contact with the facilities, without a clinical diagnosis of ICD-10 schizophrenia, and now showing signs of deteriorating clinical state after at least two months of limited or no symptoms. In the SCID interview, twenty patients were found to suffer from bipolar disorder, of whom seven (70%) of ten patients with bipolar I but only two (20%) of ten with bipolar II disorder had been previously clinically correctly diagnosed. In the present pilot study, using our Finnish translation of the Mood Disorder Questionnaire among unselected psychiatric patients, we investigated its psychometric and screening properties, and its feasibility in improving recognition of type I and II bipolar disorder. Take the Mood Disorders Questionnaire before reading this scoring page.. Hangzhou Seventh People's Hospital, Zhejiang, China, Affiliation Our study population was not a selected sample of patients with mood disorders, but rather an ordinary sample of secondary care psychiatric patients, schizophrenia excluded. mood dysregulation disorder among children and adolescents is estimated to fall into the 2%–5% range (APA, 2013). Click through the PLOS taxonomy to find articles in your field. Their mean age was 37.9 ± 11.4 years, and 56 (51%) were female. The goal of present study is comparing some of these common factors between generalized anxiety disorder and unipolar mood disorder. Google Scholar. Yes Therefore, we suggested that only part one of the MDQ (13 items of manic/hypomanic symptoms) should be scored if the MDQ is to be used as a screening tool for the patients with mood disorders in clinical settings. Nevertheless, even using the standard cut-offs several patients with previously unrecognised bipolar II disorders were identified, and in fact, ignoring the last question completely resulted in lower specificity. The instrument has so far been little investigated by others than its developers. It is to be noted that our findings are based only on ten bipolar II patients and an enriched subsample of patients with bipolar disorder. Women may experience many types of psychiatric problems after childbirth. Read the overview below to gain an understanding of this illness and explore the previews of other articles examining different aspects of depression. In BD, risks for medical disorders including diabetes or metabolic syndrome, and cardiovascular disorders, … 10.1016/S0165-0327(97)00082-7. Article  Objective Adjustment disorders are re-conceptualized in the DSM-5 as a stress-related disorder; however, besides the impact of an identifiable stressor, the specification of a stress concept, remains unclear. J Affect Disord. Because the mean MDQ score of the patients with BD-I was highest and that of UD was lowest, and MDQ could screen BD-II patients from UD patients by ROC analysis, we did not compare BD-I and UD in the ROC analysis. There were no significant differences between the enrolled patients and patients who did not participate in terms of age and sex. We suggest that the optimal cut-offs for bipolar II disorders should be further investigated in larger and representative patient samples. Several methodological limitations should be noted, some suggesting caution in interpreting the findings. Yes All authors participated in the translation of the Mood Disorder Questionnaire, plus read and approved the final manuscript. Clinical trials have indicated that the MDQ has a high rate of accuracy; it is able to identify seven out of ten people who have bipolar disorder and screen out nine out of … No, Is the Subject Area "Neuropsychological testing" applicable to this article? Despite the small sample size, the difference approached statistical significance (Fisher's exact test, p = 0.07). 2001, 67: 45-69. Part three assesses the level of functional impairment due to the symptoms on a 4-point scale (“no” to “severe”) [7], [15]. Twenty-nine (27%) subjects had negative MDQ but 4–6 positive items in question 1. The Affiliated Brain Hospital, Nanjing Medical University, Jiangsu, China, Affiliation The study protocol was approved by the Clinical Research Ethics Committees of the respective study centers. The Mood Disorder Questionnaire (MDQ) is an excellent screening tool for bipolar disorder.It is considered a gold standard screening tool in the world of bipolar disorder. Our results were similar to the results from a study in Korea. In the reliability exercise, raters' judgments of BD were compared with the best estimate clinical diagnoses [25]; the kappa values were above 0.85 for each rater. In addition, a depressive episode is usually the first mood syndrome at the onset of BD, and depressive episodes are more frequent than manic/hypomanic episodes [22], often leading to the misdiagnosis of BD as major depressive disorder (MDD), also called unipolar depression (UD). BD is a common disorder. The translated MDQ was found internally consistent (alpha 0.79) and a feasible screening tool. The feature of relatively low sensitivity (0.66) and higher specificity (0.88) in this study was similar to that of other studies as well [7], [9], [13]–[14]. The first two authors supervised the diagnostic process. It is therefore clear that the ROC-analysis overestimated sensitivity and underestimated specificity, and cannot be compared with respective estimates from unselected samples [3]. Cassano GB, Akiskal HS, Savino M, Musetti L, Perugi G: Proposed subtypes of bipolar II and related disorders: with hypomanic episodes (or cyclothymia) and with hyperthymic temperament. Some major factors involve child abuse or neglect, school failure, traumatic life experiences and brain damage. Take this bipolar test to see if you might have bipolar disorder symptoms. Table 1 displays the socio-demographic characteristics of the whole sample and separately for patients by diagnosis. The instrument was found to have relatively good sensitivity (0.73) and very good specificity (0.90) in samples comprising mostly patients with uni- and bipolar mood disorders in academic centers [3]; in a further general population study the sensitivity turned out to be very low (0.28), but specificity (0.97) remarkably high [4]. CAS  Symptoms may include extreme sadness, low energy, anxiety, crying episodes, irritability, and changes in sleeping or eating patterns. The diagnosis of BD-II need one or more hypomanic episodes (without manic episode) and one or more major depressive episode. The questionnaire takes about five minutes to complete, and can provide important insights into diagnosis and treatment. The internal consistency of the translated instrument was almost as good (Cronbach's alpha 0.79 vs. 0.90) as in the original validation study . As the predominant psychopathology even in treated BD, depression is associated not only with excess morbidity, but also mortality from co-occurring general-medical disorders and high suicide risk. The results of the Korean study were similar to ours. https://doi.org/10.1371/journal.pone.0091895.g002. Less than half of those diagnosed with bipolar disorder in the SCID interview had had a ICD-10 diagnosis of bipolar disorder, mania or hypomania, or bipolar schizoaffective disorders before the interview. In a pilot study for the Jorvi Bipolar Study (JoBS), 109 consecutive non-schizophrenic psychiatric out- and inpatients in Espoo, Finland, were screened for bipolar disorder using the Finnish translation of the MDQ, and 38 of them diagnostically interviewed with the SCID. The Mood Disorder Questionnaire [3] is a short self-report screening instrument, and was translated into Finnish by the authors. In part one, the MDQ screens for a lifetime history of manic/hypomanic symptoms using 13 yes/no items. 1997, Washington, DC, American Psychiatric Press. Our findings support the value and feasibility of screening for bipolar disorder with the MDQ in psychiatric settings. 2. It asks: 1. if you've experienced any of 13 specific behaviors associated with bipolar disorder 2. if the symptoms you checked in question one occurred at the same time 3. about the severity of your symptoms 4. about your family's history of mental illness 5. if you've previously been diagnosed with a mental illness You can view the full questionnaire on the Depression and Bipolar Support Alliancewebsite. Contributed reagents/materials/analysis tools: HCY. The subspecialties of psychiatry and gynecology have developed overlapping but distinct diagnoses that qualify as a premenstrual disorder… The Mood Disorder Questionnaire (MDQ) is a well-recognized screening tool for bipolar disorder, but its Chinese version needs further validation. In this study, we found that if only part one of MDQ was used, MDQ could differentiate between BD and UD, between BD-II and UD, and between BD-I and BD-II. The questionnaire is self-administered and comprised of 5 questions. Peer mentor programs (PMPs) have been associated with reduced psychiatric hospitalisation and shorter lengths of stay for those with other severe mental illnesses. Ghaemi SN, Boiman EE, Goodwin FK: Diagnosing bipolar disorder and the effect of antidepressants: a naturalistic study. 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